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What Is CBCA?

Understanding CBCA: An Overview

CBCA, also known as cannabichromenic acid, is a chemical precursor to CBC, one of the many cannabinoids found in the cannabis plant. While CBCA has not been extensively researched, it shows promise in the realm of cannabinoid science.

What Sets CBCA Apart

As a cannabinoid acid, CBCA differs from cannabinoids in the presence of an additional carboxyl group, allowing it to have unique effects on the body. It is derived from CBGA, the “mother cannabinoid,” through a specific enzymatic reaction catalysed by a specialised enzyme called cannabichromenic acid synthase (CBCAS).

The Path to CBC

Further conversion of CBCA results in the creation of other cannabinoids such as CBC, CBLA, and eventually CBL. CBC, discovered in 1966, is one of the major phytocannabinoids found in cannabis and shows potential therapeutic properties. Even though CBCA is low in concentration in cannabis, its potential uses are being explored.

Possible Health Benefits

Research on the benefits of CBCA is limited, but it is believed to share non-psychoactive traits with CBC. CBC has shown promise in interacting with the endocannabinoid system’s CB2 receptor and TRP channels. Future studies may reveal the therapeutic potential of CBCA.

Legal Implications

CBCA is not currently regulated by most drug laws, and commercial products containing high levels of CBCA are not widely available. However, as the legal status of cannabis and hemp changes, the legal outlook for CBCA may also fluctuate in the future.

Sources

[1] Degenhardt, F., Stehle, F., & Kayser, O. (2017). The Biosynthesis of Cannabinoids. Handbook of Cannabis and Related Pathologies, 13-23. [Source]

[2] Pollastro, F., Caprioglio, D., del Prete, D., Rogati, F., Minassi, A., Taglialatela-Scafati, O., Munoz, E., & Appendino, G. (2018). Cannabichromene. Natural Product Communications, 13(9), 1934578X1801300. [Source]

[3] Iwata, N., & Kitanaka, S. (2011). New Cannabinoid-Like Chromane and Chromene Derivatives from Rhododendron anthopogonoides. Chemical and Pharmaceutical Bulletin, 59(11), 1409-1412. [Source]

[4] Russo, E. B., & Marcu, J. (2017). Cannabis Pharmacology: The Usual Suspects and a Few Promising Leads. Cannabinoid Pharmacology, 67-134. [Source]