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Is CBD A Placebo?

Is CBD Just a Placebo Effect?

There has been ongoing discussion and debate surrounding whether CBD (cannabidiol) actually produces physiological changes within the body or if its effects are simply a result of the placebo effect. But, scientific studies have shown that CBD does, in fact, cause real and measurable changes in the body.

Understanding the Placebo Effect

Before diving into the research, it’s important to understand what the placebo effect actually is. In simple terms, the placebo effect refers to the beneficial effects produced by an ineffective drug or treatment. These positive outcomes are often attributed to the patient’s belief in the treatment rather than the treatment itself. While the placebo effect may not cure serious conditions, it can improve symptoms related to pain, sleep disorders, depression, and more.

CBD Goes Beyond Placebo

Researchers have conducted various studies to determine whether the effects of CBD are distinct from those of a placebo. In placebo-controlled trials, one group receives the substance being tested (experimental group) while another receives a fake version (placebo group). Double-blind, placebo-controlled studies take this a step further by keeping both the patients and researchers unaware of who receives the substance and who receives the placebo.

These controlled studies have shown that CBD offers more than just a placebo effect. For example, studies on patients with seizures, Parkinson’s disease, and ulcerative colitis have demonstrated that the effects of CBD are far superior to those of a placebo. Patients who received CBD experienced a significant reduction in seizure frequency, improved quality of life, and better symptomatic treatment compared to those who received a placebo.

More Research Needed

While the existing studies provide valuable insights into the effects of CBD, more research is needed to fully understand its potential benefits. With further well-designed studies, we can gain a better understanding of how CBD works and its efficacy in treating various conditions. As new research emerges, it will shed more light on the true effects of CBD versus placebo.

Sources

[1] Thiele, E. A., Marsh, E. D., French, J. A., Mazurkiewicz-Beldzinska, M., Benbadis, S. R., Joshi, C., Lyons, P. D., Taylor, A., Roberts, C., & Sommerville, K. (2018, March 17). Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial. SCIENCE DIRECT. [Source]

[2] Chagas, M. H., Zuardi, A. W., Tumas, V., Pena-Pereira, M. A., Sobreira, E. T., Bergamaschi, M. M., dos Santos, A. C., Teixeira, A. L., Hallak, J., & Crippa, J. A. (2014, September 18). Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial. SAGE Journals. [Source]

[3] Irving, P. M., Iqbal, T., Nwokolo, C., Subramanian, S., Bloom, S., Prasad, N., Hart, A., Murray, C., Lindsay, J. O., Taylor, A., Barron, R., & Wright, S. (2018, March 10). A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis. Inflammatory Bowel Diseases. [Source]