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How Does Your Body Absorb CBD?

Understanding Bioavailability: How Your Body Absorbs CBD

Have you ever wondered how your body absorbs CBD? The key to understanding this process lies in bioavailability, which refers to the rate at which active ingredients like CBD reach their target area in the body. In the case of CBD, the target area is the bloodstream. If you wanted to maximize bioavailability, the most direct method would be intravenous administration of CBD. However, this method is not always feasible or practical.

For every obstacle introduced (such as digestive enzymes, stomach acid, and metabolism), the rate and extent to which CBD reaches the bloodstream are compromised. This means that not all of the CBD you consume will actually make it to your bloodstream. The intensity and effectiveness of CBD products largely depend on their bioavailability.

The Different Ways to Take CBD and Their Bioavailability

There are various ways to consume CBD, each with its own benefits and bioavailability rates. Oral consumption of CBD is the most popular method, but it has a lower bioavailability (around 4-20%) compared to other methods. Sublingual administration, which involves placing CBD drops under the tongue, offers increased bioavailability compared to oral ingestion.

CBD topicals, such as creams applied to the skin, have the lowest bioavailability (5-10%) but can still be effective for localized relief. Vaporizing CBD, by inhaling vape liquids, provides a quick hit of CBD with a bioavailability rate of approximately 50-80%, making it one of the most effective methods of consumption.

Improving Bioavailability: Tips and Tricks

There are ways to enhance the bioavailability of CBD products. For example, liposomes are microscopic vesicles that help protect CBD from digestive enzymes, improving its absorption rate. Nanoemulsion is another method that breaks down CBD into smaller particles for better absorption.

Consuming CBD with a high-fat meal can also increase its bioavailability, as CBD is lipophilic and dissolves in fat. By understanding these techniques and choosing the right administration method, you can ensure that your body absorbs CBD more effectively.

Conclusion

While bioavailability is an essential factor to consider when choosing a CBD product, it is not the only consideration. Quality, dosage, and individual needs all play a role in determining the effectiveness of CBD. By selecting the right method of consumption, whether oral, sublingual, topical, or vaporizing, you can maximize the bioavailability of CBD and experience its benefits to the fullest.

Sources

[1] Huestis, M. A. (2090). Human Cannabinoid Pharmacokinetics. NCBI. [Source]

[2] Hammell, D. C., Zhang, L. P., & Ma, F. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. NCBI. [Source]

[3] Lanz, C., Mattsson, J., & Soydaner, U. (2016). Medicinal Cannabis: In Vitro Validation of Vaporizers for the Smoke-Free Inhalation of Cannabis. NCBI. [Source]

[4] Birnbaum, A. K., Karanam, A., & Marino, S. E. (2019). Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy. PubMed. [Source]