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Can you take CBD alongside other supplements?

Can You Take CBD Alongside Other Supplements?

While CBD is a worthy supplement in its own right, how well does it work alongside traditional dietary supplements? Keep reading as we take a closer look at possible interactions and find out if combining CBD with supplements is safe.

Does CBD Interact with Dietary Supplements?

Based on our current understanding of CBD’s interactions with supplements, the cannabinoid doesn’t appear to impact the human body negatively. Additionally, a World Health Organization (WHO) review found that ‘CBD is generally well tolerated with a good safety profile’. They did note CBD’s potential drug-drug interactions, but this may not impact vitamins and minerals negatively.

What is CBD?

CBD comes from the Cannabis sativa L. species, and is one of over a hundred cannabinoids found inside the plant. These cannabinoids are unique because they can interact with the human body via a vast network of receptors, influencing mental and physical well-being.

What Are Dietary Supplements?

Dietary supplements are monitored and regulated by either the Food & Drug Administration (US) or the European Commission (EU). They include categories such as vitamins and minerals, botanical and herbal substances, amino acids, and enzymes.

The Link Between CBD and Dietary Supplements: Enzyme CYP450

CBD’s processing in the body involves the enzyme CYP450, which also affects how fast or slow other substances are broken down. This interaction may impact the effectiveness of other supplements and medications in the body.

Should You Combine CBD with Other Supplements?

While it’s important to proceed with caution, current knowledge suggests that CBD may not negatively interact with certain vitamins and minerals. Some combinations, like CBD with vitamin D3 or melatonin, may even have beneficial outcomes. Always introduce combinations gradually and consider the specific influence of each supplement.

Is Combining CBD with Supplements Safe?

Combining CBD with various supplements is generally considered safe, but it’s important to be mindful of every interaction. Always prioritize a healthy and active lifestyle, using supplements and CBD as aids to address specific well-being needs.

Sources

[1] WHO | cannabidiol critical review. [Source]

[2] Petrescu NB, Jurj A, Sorițău O, et al. Cannabidiol and Vitamin D3 impact on osteogenic differentiation of human dental mesenchymal stem cells. [Source]

[3] Dietary supplements. U.S. Food and Drug Administration. [Source]

[4] Food supplements. Food Safety. European Commission. [Source]

[5] Alagbonsi IA, Olayaki LA. Role of oxidative stress in Cannabis Sativa-associated spermatotoxicity: Evidence for ameliorative effect of combined but not separate melatonin and Vitamin C. Middle East Fertility Society Journal. [Source]

[6] Omega-3 supplements: In depth. National Center for Complementary and Integrative Health. [Source]

[7] Costello RB, Lentino CV, Boyd CC, et al. The effectiveness of melatonin for promoting healthy sleep: A rapid evidence assessment of the literature. Nutrition journal. [Source]