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Can You Take CBD Alongside Other Medication?

Can You Take CBD Alongside Other Medication?

In today’s modern age, it is not uncommon for us to take a variety of different medications. Given CBD’s influence on several biological systems, knowing whether it can be taken alongside these regular medications is an important topic. Keep reading for everything you need to know.

Current Research Shows CBD has an Excellent Safety Record

The different ways in which CBD can support the body continue to be unveiled, but one factor remains constant—the compound’s favourable safety record. CBD is well tolerated, even in doses of up to 160mg a day, with minimal side effects. To put that in perspective, an average dose of CBD oil is 3–4 drops three times a day; this totals approximately 42mg/day. Furthermore, the compound has been acknowledged as showing a good level of safety by the World Health Organization in their in-depth review. Their conclusion of current CBD research was the following: “CBD is generally well tolerated with a good safety profile. Reported adverse effects may be the result of drug-drug interactions between CBD and patients’ existing medications”. The review took into account a broad range of research papers, alongside clinical and preclinical trials. Their findings are encouraging because it outlines that, based on what we currently understand, the side effects of CBD appear minimal.

The Long-Term Safety of CBD Extracts

There does, however, remain a question around the long-term safety of CBD. With many studies still in preclinical stages, we don’t fully understand every possible interaction, complication, or side effect that could occur inside the human body. Changes are underway to establish a baseline safety for all CBD extracts. European regulators have classified CBD and its derivatives as a novel food, meaning all CBD products must adhere to strict production standards and an extensive approval process. These new principles will provide a framework for the entire CBD industry and help reduce the risk of unsafe or low- quality CBD products entering the market.

Understanding the Relationship Between CBD and Medication

CBD, like many forms of medication, needs to be metabolised by the liver before it can be distributed around the body. Once the digestive system has processed CBD, it will go through a “first-pass” process in the liver, using special enzymes to break the CBD down into smaller components. When consumed alongside other medication, CBD can take all of the liver’s attention, affecting the breakdown of other medication. Research into the potential interaction between CBD and medication is ongoing.


[1] Bergamaschi, M. M., Costa Queiroz, R. H., S. Crippa, J. A., & Zuardi, A. W. (2011). Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent. Medicinal Genomics. [Source]

[2] World Health Organization. (2018). CANNABIDIOL (CBD). [Source]